(a) Griffith's experiment with Pneumococcus suggests that genetic material is responsible for transforming bacteria.
Molecular Basis of Inheritance
(c) In DNA adenine always pairs with thymine and guanine always pairs with cytosine, this is called complementary base pairing.
(a) Kim et al (1973) suggested L shape model of t-RNA by X-Ray diffraction while studying phenyl alanine t-RNA of yeast.
(c) Ribozymes are catalytically active RNA molecule discovered in 1980s.
They are self splicing introns indicating their possible role as intermediates in the evolution of biological systems from abiotic substances.
(a) Colour blindness follows sex-linked inheritance. Phenylketonuria is an in born error of metabolism.
(d) Alfred Hershey and Martha Chase studied bacteriophages, or viruses that attack bacteria.
In 1952, they conducted a series of experiments to prove that DNA is the genetic material.
They labelled the protein of bacteriophages with radioactive sulphur and their DNA with radioactive phosphorus.
(a) DNA fingerprinting is a technique to identify a person on the basis of his DNA which is specific for every individual.
This technique for the first time was developed by Alec Jeffreys and his colleagues at Leicester University in U.K.
DNA of an individual carries specific sequences of nucleotides which are repeated many times throughout the length of DNA.
This reveals polymorphism in DNA.
These are inherited.
Each individual inherits these repeats from his/her parents which are used as genetic markers in personal identity test.
(a) DNA fingerprinting is the technique of determining nucleotide sequences of certain areas of DNA which are unique to each individual.
DNA contains noncistronic hypervariable repeat sequences called VNTR.
DNA fingerprinting involves the identification of these VNTRs.
(c) Satellite DNA is useful in forensic science.
The polymorphism of minisatellite, microsatellite and minivariant repeats is analysed for DNA finger printing, DNA profiling.
It helps in the resolution of crimes, legal disputes etc.
(c) Common activities in bioinformatics include mapping and analysing DNA and protein sequences, aligning different DNA etc. are the part of human genome project.