(b) Thalassemia is a quantitative defect (less globin synthesized); sickle cell anaemia is a qualitative defect (abnormal globin).
Principles of Inheritance and Variation
(c) Klinefelter syndrome (47,XXY) affects males — small testes, gynecomastia, infertility.
(b) Sickle cell anaemia is autosomal recessive, caused by mutation in beta-globin gene on chromosome 11.
(d) O-group child has genotype I^O I^O; must have received I^O from father; father must be I^B I^O.
(a) A dominant allele expresses itself in both homozygous and heterozygous conditions.
(a) Epistasis: one gene pair suppresses the expression of a non-allelic gene pair.
(b) AABbCc: A is fixed; Bb gives B or b; Cc gives C or c → 2×2 = 4 gamete types.
(b) Three genomes: nuclear, mitochondrial, and chloroplast.
(d) Crossing over between non-sister chromatids of homologs causes recombination of linked alleles.
(c) A woman passes one X chromosome to all children — both sons and daughters can inherit it.