(d) Haemophilia is X-linked recessive; hemizygous males express the recessive allele.
Principles of Inheritance and Variation
(d) Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism.
(b) A colour blind girl needs X^c X^c: X^c from father (colour blind) and X^c from mother (carrier, whose father was colour blind).
(d) ABO blood groups are controlled by three multiple alleles: I^A, I^B, I^O.
(a) Man is Bb (heterozygous); woman is bb. Cross: Bb × bb = 1 Bb (brown) : 1 bb (blue) = 1:1.
(d) Non-disjunction of chromosome 21 during meiosis causes trisomy 21 (Down syndrome).
(c) Turner syndrome (45,X): monosomy X in females.
(a) Homologous chromosomes separate during anaphase I of meiosis.
(c) Mother is a carrier (X^H X^h) — half sons haemophilic, half daughters carriers.
(a) Colour blind mother (X^c X^c) × normal father (XY): sons all colour blind; daughters all carriers.